anandamide vs. 2-AG
Anandamide and 2-AG bind to the cannabinoid receptors CB1 and CB2, which are the most widely-studied cannabinoid receptors. CB1 receptors are located in the central nervous system and regulate a wide variety of brain functions such as the release of neurotransmitters like serotonin, dopamine, and glutamate. CB2 receptors, which mostly exist on immune cells, play an important role in neuroprotection, neuroinflammation and pain reduction.
